尼古丁袋的健康风险评估(Health risk assessment of nicotine pouches)

尼古丁袋是一种新型的无烟草产品,含有由尼古丁盐和填充材料组成的粉末。德国联邦风险评估研究所(BfR)根据现有研究和数据评估了这些产品的健康风险。该更新评估包括对BfR进行的实验研究的评估。药代动力学研究表明,烟袋中至少一半的尼古丁可以被吸收。血液中尼古丁含量达到了相关水平,即与传统香烟的水平相当。使用高剂量产品导致尼古丁水平明显高于香烟消费。德国政府将尼古丁袋归类为“新型食品”。…

尼古丁袋是一种新型的无烟草产品,含有由尼古丁盐和填充材料组成的粉末。德国联邦风险评估研究所(BfR)根据现有研究和数据评估了这些产品的健康风险。该更新评估包括对BfR进行的实验研究的评估。药代动力学研究表明,烟袋中至少一半的尼古丁可以被吸收。血液中尼古丁含量达到了相关水平,即与传统香烟的水平相当。使用高剂量产品导致尼古丁水平明显高于香烟消费。德国政府将尼古丁袋归类为“新型食品”。

Health risk assessment of nicotine pouchesUpdated BfR Opinion no. 023/2022, 7 October 2022Nicotine pouches are new, tobacco-free products that contain a powder made up of nicotinesalts and filling materials. The German Federal Institute for Risk Assessment (BfR) has assessed the health risks from these products based on existing studies and data. This updatedassessment includes an evaluation of experimental studies conducted by the BfR. Pharmacokinetic studies show that at least half of the nicotine in the pouch can be absorbed. Relevantnicotine blood levels were achieved, i.e. levels were within a range that is comparable withconventional cigarettes. Use of high-dose products led to significantly higher nicotine levelsthan cigarette consumption. The German state authorities classify nicotine pouches as a‘novel food’.

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